Research

NSSI Research
Longitudinal machine learning prediction of non-suicidal self-injury among Chinese adolescents: A prospective multicenter cohort study
Guo, X., Liu, S., Jiang, L., Xiong, Z., Wang, L., Lu, L., ... & Daniel T.L. Shek
Journal of Affective Disorders, 2025, 120110. [Q1, IF: 4.9]
code / paper

We introduce a progressive prediction framework utilizing four waves of longitudinal data and seven machine learning algorithms to predict NSSI risk among 3,483 Chinese adolescents.

Causal Analysis Research
Factors and pathways of non-suicidal self-injury in children: Insights from computational causal analysis
Guo, X., Wang, L., Li, Z., Feng, Z., Lu, L., Jiang, L., & Zhao, L.
Frontiers in Public Health, 2024, 12, 1305746. [Q1, IF: 3.4]
project / paper

Utilizing computational causal analysis to identify key factors and pathways contributing to non-suicidal self-injury behaviors in children, providing insights for intervention strategies.

CRISP Framework
CRISP: A causal relationships-guided deep learning framework for advanced ICU mortality prediction
Wang, L., Guo, X., Shi, H., Ma, Y., Bao, H., Jiang, L., Zhao, L., Feng, Z., Zhu, T., & Lu, L.
BMC Medical Informatics and Decision Making, 2025, 25(1), 165. [Q2, IF: 3.8]
code / paper

A novel deep learning framework that leverages causal relationships to improve mortality prediction in intensive care units, demonstrating superior performance over traditional approaches.

COVID-19 Study
Life changes and symptoms of depression and anxiety among Chinese children and adolescents before, during, and after the COVID-19 pandemic lockdown: a combination of cross-sectional, longitudinal, and clustering studies
Zeng, Y., Song, J., Zhang, Y., Guo, X., Xu, X., Fan, L., Zhao, L., Song, H., & Jiang, L.
European Child & Adolescent Psychiatry, 2025, 34(3), 1025-1038. [Q1, IF: 4.9]
project / paper

A comprehensive analysis of mental health changes in Chinese youth during the COVID-19 pandemic, combining multiple study designs to understand the impact of lockdown measures on depression and anxiety symptoms.

Cognitive Impairment Research
Dynamic causal graph-based learning approach for predicting cognitive impairment in middle-aged and older adults
Wang, L., Guo, X., Zhou, Y., Li, Z., Jiang, L., Zhao, L., Feng, Z., & Lu, L.
In Proceedings of the 46th Annual Conference of the Cognitive Science Society, 2024, Vol. 46. [Conference]
paper

A dynamic causal graph-based machine learning approach for predicting cognitive impairment in aging populations, incorporating temporal relationships and causal mechanisms for improved accuracy.

Granger Causality Study
Prediction of cognitive impairment in middle-aged and elderly people: A method based on Granger causality
Li, S., Wang, L., Guo, X., Shi, H., Ma, Y., Zhang, X., Feng, Z., & Lu, L.
In Proceedings of the 47th Annual Conference of the Cognitive Science Society, 2025, Vol. 47. [Conference]
paper

A novel approach utilizing Granger causality methods for predicting cognitive impairment in middle-aged and elderly populations, focusing on temporal causal relationships in cognitive decline.

MDRO Study
Causality-Informed Models for Multidrug-Resistant Organism Prediction: Enabling Effective ICU Antibiotic Stewardship
Wang, L., Guo, X., Chen, Y., Li, S., Zhao, L., Feng, Z., & Lu, L.
International Journal of Antimicrobial Agents, 2026, 107767. [Q1, IF: 4.6]
code / paper

Development of causality-driven predictive models for multidrug-resistant organism (MDRO) infections in ICU settings, aimed at improving antibiotic stewardship programs and reducing healthcare-associated infections.

Academic Values Study
Academic values, academic anxiety, and non-suicidal self-injury in Chinese adolescents: A three-wave longitudinal study
Xinyu Guo, Peng, Y., Li, X., Zhao, L., Jiang, L., & Shek, D. T. L.
BMC Psychology, 2025. (Under review)

A longitudinal investigation examining the relationships between academic values, academic anxiety, and non-suicidal self-injury behaviors among Chinese adolescents across three time points.